Background: Recurrent Klebsiella pneumoniae pyogenic liver abscess (KPLA) is clinically important because persistent or recurrent cavities may reflect ongoing infection, inadequate source control, or an occult gastrointestinal lesion. We aimed to develop a simple, literature-in [....] » Read More
Background: Postoperative pelvic fluid collections after hysterectomy commonly trigger empiric broad-spectrum antimicrobial therapy, yet sterile postoperative collections and topical hemostatic agents may mimic abscess on imaging. We used a solved postoperative gynecologic oncolo [....] » Read More
Background: Solved clinical cases can be converted into worked examples—cases with a known diagnosis and outcome that are used to teach clinical reasoning—but building these from real records is time-intensive. We developed a mentored AI workflow to transform a de-ide [....] » Read More
Background: Infectious-disease management requires clinicians to integrate host factors, epidemiology, examination, laboratory and imaging data, microbiology, treatment response, antimicrobial stewardship, prevention, and communication under uncertainty. Yet learners have limited [....] » Read More
Summary: Acinetobacter junii is a rarely reported cause of human infection. We report a case of A.junii bacteremia in a 79-year-old man with end-stage renal disease on hemodialysis who presented with lower extremity cellulitis and sepsis. Blood cultures obtained prior to antibiot [....] » Read More
Title : Diagnostic approaches, predictive and prognostic assessments, monitoring, treatment & management of infectious diseases and disease prevention
Sergey Suchkov, N.D. Zelinskii Institute for Organic Chemistry of the Russian Academy of Sciences & InMedStar, Russian Federation
A new and upgraded approach to the diseased states and wellness, and to re-shape tomorrow’s healthcare, whilst doing it today, resulted in a new global trend in the healthcare services, namely, Personalized and Precision Medicine (PPM). PPM as a Unique Entity demonstrating [....] » Read More
Title : The accelerated timeline: Human ecology, climate change, and the next global outbreak
Claudia Ferreira, Sorbonne University, France
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Title : Climate changes & increasing pollution and respiratory illnesses
Yazdan Mirzanejad, University of British Columbia, Canada
Climate change, global warming, and environmental pollution are increasingly recognized as major drivers of respiratory morbidity and mortality worldwide. Rising temperatures, more frequent wildfires, prolonged pollen seasons, desert dust, ground-level ozone, and exposure to fine [....] » Read More
Title : Invasive group A streptococcal infections in children: Current therapeutic challenges
Elena Chiappini, University of Florence, Italy
Group A Streptococcus (GAS) is responsible for a broad spectrum of infections in children, ranging from common and usually self-limiting diseases to rapidly progressive and life-threatening invasive infections. Invasive GAS (iGAS) disease includes bacteremia, pneumonia, osteoarti [....] » Read More
Title : Climate changes & increasing tickborne illnesses
Yazdan Mirzanejad, University of British Columbia, Canada
Climate change is reshaping the epidemiology of tick-borne diseases by altering vector survival, seasonal activity, geographic distribution, and interactions among ticks, wildlife, domestic animals, and humans. Warmer temperatures, milder winters, prolonged vegetation periods, an [....] » Read More
Title : Efficacy and safety of Tegoprazan–Amoxicillin dual therapy versus bismuth-containing quadruple therapy for helicobacter pylori eradication: A systematic review and meta-analysis
Alaa Babonji, Ministry of National Guard Health Affairs, Saudi Arabia
Helicobacter pylori infection but is limited by treatment complexity and adverse events. Tegoprazan, a potassium-competitive acid blocker (P-CAB), has emerged as a promising alternative due to its potent acid-suppressive properties. We conducted a systematic review and meta-analy [....] » Read More