Title : A novel device for preventing ventilator-associated pneumonia in intubated patients
Abstract:
Background: Ventilator-Associated Pneumonia (VAP) occurs within 48 hours of mechanical ventilation and up to 48 hours after extubation, often caused by bacterial pathogens such as Staphylococcus aureus, Pseudomonas aeruginosa, and Klebsiella pneumoniae etc in the secretion above the balloon around of the tube. Traditional prevention methods, such as antibiotics and regular suctioning, have limitations in removing bacteria from sputum during intubation. This device aims to use 222nm UV-C light to more effectively kill pathogens in the secretion above the balloon, in order to reduce the risk of VAP.
Materials and Methods: The device uses a combination of 222nm UV-C light and fiber optics to deliver light to the sputum area around the endotracheal tube and secretions above the balloon. The 222nm UV-C light kills pathogens without harming human tissues. The fiberoptics are arranged in a helical pattern around the tube to ensure even light distribution, while a reflective membrane lay under the fiberoptics prevents UV light from entering the tube and forming harmful ozone. Additionally, a negative pressure suction system continuously removes ozone and secretions during treatment.
Results: The device effectively disinfects the sputum, ensuring a high level of pathogen elimination. The 222nm UV-C light method overcomes the challenge of sputum viscosity, ensuring consistent treatment. The design also minimizes the risk of ozone production, a common issue with UV sterilization.
Discussion: This innovation provides a non-chemical method that targets bacteria in the sputum without introducing the risk of antibiotic resistance. It ensures patient safety by minimizing harmful ozone production.
Conclusion: The novel intratracheal tube with UV-C light sterilization device offers a promising solution to prevent VAP in intubated patients, providing a valuable complement to existing prevention methods.
