Acinetobacter species constitute a diverse group of Gram-negative bacteria that are ubiquitous in nature, found in various environments, including soil, water, and hospital settings. Acinetobacter baumannii, a clinically significant species within this genus, has emerged as a notorious opportunistic pathogen responsible for various healthcare-associated infections. Its ability to persist on surfaces and medical equipment, coupled with resistance to desiccation and disinfectants, contributes to its prevalence in hospital environments. Acinetobacter baumannii is associated with a range of infections, including ventilator-associated pneumonia, bloodstream infections, urinary tract infections, and wound infections. The bacteria often affect individuals with compromised immune systems, and their ability to develop multidrug resistance poses a substantial challenge in clinical management. Strains of Acinetobacter baumannii carrying carbapenemase genes further complicate treatment, limiting the available options for effective antibiotics. Efforts to control Acinetobacter infections involve strict adherence to infection prevention measures, such as hand hygiene, environmental cleaning, and surveillance. Ongoing research focuses on understanding the mechanisms of antibiotic resistance in Acinetobacter species and developing innovative therapeutic strategies to combat these resilient pathogens.
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