Antibiotic resistance stands as a multifaceted challenge imperiling global public health. Over decades of antibiotic use and misuse, bacteria have evolved mechanisms to withstand the drugs designed to eliminate them. The misuse of antibiotics in agriculture, healthcare, and self-medication has accelerated this process, fostering the emergence of resilient bacterial strains. Resistance mechanisms include the acquisition of genetic mutations and the exchange of resistance genes among bacteria through horizontal gene transfer. In healthcare settings, the overprescription and inappropriate use of antibiotics contribute significantly to resistance development. Methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant tuberculosis are stark examples of bacteria that have evolved formidable resistance, rendering conventional treatments ineffective. The dire consequences of antibiotic resistance include prolonged illnesses, increased healthcare costs, and elevated mortality rates. Addressing this crisis demands a multifaceted approach, incorporating responsible antibiotic use, surveillance, development of new antibiotics, and global collaboration to curb the spread of resistant strains.
Title : Extensively drug-resistant bacterial infections: Confronting a global crisis with urgent solutions in prevention, surveillance, and treatment
Yazdan Mirzanejad, University of British Columbia, Canada
Title : Pathogen-derived noncanonical epitopes: Are they valuable targets for novel vaccinations and shall we be concerned about autoimmune responses?
Michele Mishto, Francis Crick Institute, United Kingdom
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Claudia Ferreira, Sorbonne University, France
Title : Measles vaccination coverage indicators in 2023 and advance towards measles elimination and eradication by 2030
Pedro Plans Rubio, College of Physicians of Barcelona, Spain
Title : Gendered socioeconomic impacts of emerging infectious diseases: Insights from a mixed-methods study in Guinea
Stephanie Maltais, University of Montreal, Canada
Title : The role of social sciences in operationalizing the One Health approach: A case study of the DOPERAUS project in Guinea and the Democratic Republic of Congo
Stephanie Maltais, University of Montreal, Canada