Blastocystosis is a gastrointestinal infection caused by the protozoan parasite Blastocystis hominis. This single-celled organism is commonly found in contaminated water and food, making it a prevalent cause of intestinal infections in humans. The clinical presentation of blastocystosis varies widely, with some individuals remaining asymptomatic while others experience symptoms such as abdominal pain, diarrhea, bloating, and nausea. The transmission of Blastocystis hominis occurs through the ingestion of cysts, which are the dormant and infective stage of the parasite. Risk factors for infection include poor sanitation, consumption of contaminated water or food, and close contact with infected individuals. Diagnosis of blastocystosis involves the identification of Blastocystis hominis cysts or trophozoites in stool samples. However, the interpretation of diagnostic results can be challenging due to the variable clinical significance of the parasite. In some cases, Blastocystis hominis is considered a commensal organism, while in others, it may contribute to gastrointestinal symptoms. Treatment options for symptomatic cases often involve antimicrobial agents, such as metronidazole or other antiprotozoal medications. However, controversies surround the interpretation of treatment efficacy, as some individuals may continue to harbor the parasite despite clinical resolution.
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