Meningitis is an inflammation of the meninges, the protective membranes surrounding the brain and spinal cord, often caused by infectious agents. The most common etiological agents are bacteria, viruses, fungi, and, less frequently, parasites. Bacterial meningitis, particularly caused by Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae, is associated with severe outcomes and requires urgent medical attention. Clinical presentation of meningitis includes symptoms such as sudden onset of fever, severe headache, neck stiffness, and photophobia. In bacterial meningitis, additional signs may include altered mental status, seizures, and a characteristic purpuric rash in the case of meningococcal infection. Viral meningitis tends to have a milder course, resembling flu-like symptoms. Diagnosis involves a lumbar puncture to analyze cerebrospinal fluid (CSF) for signs of inflammation, cell count, and pathogen detection. Blood cultures, imaging studies, and polymerase chain reaction (PCR) tests aid in identifying the causative agent. Early diagnosis is critical for prompt initiation of appropriate treatment.
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