Scarlet fever is an infectious disease characterized by a distinctive rash, sore throat, and fever. It is primarily caused by group A Streptococcus bacteria, particularly Streptococcus pyogenes. The bacteria produce toxins that contribute to the characteristic scarlet-red rash, which feels like sandpaper when touched. Scarlet fever often occurs as a complication of streptococcal throat infections, such as strep throat. The clinical features of scarlet fever include a sore throat, fever, and a rash that typically begins on the neck and chest before spreading to other parts of the body. Other symptoms may include a strawberry-like appearance of the tongue, known as "strawberry tongue," and the presence of Pastia's lines (reddened lines in the skin folds). Historically, scarlet fever was a major cause of morbidity and mortality, especially in the 19th century. However, with the advent of antibiotics, such as penicillin, the severity and incidence of scarlet fever significantly declined. While scarlet fever remains a concern, modern medical interventions have transformed it from a life-threatening disease into a generally manageable and treatable condition.
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