Upper respiratory infections (URIs) encompass a group of illnesses affecting the upper respiratory tract, including the nose, throat, sinuses, and larynx. Commonly referred to as the "common cold," URIs are typically caused by viruses, with rhinoviruses being the most prevalent. Other viral culprits include coronaviruses, adenoviruses, and influenza viruses. Bacterial infections, such as those caused by Streptococcus pyogenes, can also lead to upper respiratory tract infections, particularly in the case of bacterial pharyngitis (strep throat). URIs are highly contagious and spread through respiratory droplets, often in crowded places or close personal contact. Clinical features of URIs include sneezing, nasal congestion, runny nose, sore throat, cough, and, in some cases, fever. Most cases are self-limiting, resolving within a week to ten days, but severe cases or complications can occur, especially in vulnerable populations like the elderly or those with compromised immune systems. Management of URIs focuses on symptom relief and supportive care. Over-the-counter medications may be used to alleviate symptoms, while rest, hydration, and maintaining good respiratory hygiene are essential components of recovery. Antibiotics are not effective against viral URIs and are reserved for bacterial infections when warranted.
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