Vaccines and immunology are pivotal in the prevention and combat of infectious diseases, leveraging the body's immune system. Antimicrobials, encompassing antibiotics, antivirals, and antifungals, serve as crucial tools for infection treatment, yet their excessive use and misuse contribute to the emergence of drug-resistant pathogens. Recognizing the intricate relationship between vaccines, immunology, and antimicrobials is essential for upholding global health. Vaccines operate by stimulating the immune system to identify and memorize specific pathogens, priming the body for a swift and effective response upon subsequent exposure. Typically containing weakened or inactivated forms of the targeted pathogen, vaccines trigger the production of antibodies and memory cells, crucial for preventing or mitigating the severity of future infections. Immunology, delving into the immune system's study, unveils the intricate network of cells, tissues, and molecules collaborating to shield the body from pathogens. Comprising innate and adaptive components, the immune system's innate defenses provide immediate, nonspecific protection, while adaptive responses involve specific pathogen recognition and the development of immunological memory. Antimicrobials, in contrast, directly eliminate microorganisms. Antibiotics disrupt essential bacterial processes, antivirals target viruses, and antifungals combat fungi. Although antimicrobials are vital for infection treatment, their inappropriate use and overprescription foster the emergence of drug-resistant strains, posing a substantial global health risk.
Title : Extensively drug-resistant bacterial infections: Confronting a global crisis with urgent solutions in prevention, surveillance, and treatment
Yazdan Mirzanejad, University of British Columbia, Canada
Title : Pathogen-derived noncanonical epitopes: Are they valuable targets for novel vaccinations and shall we be concerned about autoimmune responses?
Michele Mishto, Francis Crick Institute, United Kingdom
Title : Bioterrorism through the ages: Historical perspective, emerging threats, and medical countermeasures
Claudia Ferreira, Sorbonne University, France
Title : When acute EBV mimics HIV: A case of false positive p24 antigen and low-level HIV antibody reactivity
Smriti Chaudhary, Imperial College Healthcare NHS Trust, United Kingdom
Title : OnePeru: Peruvian bioinformatics platform to contribute to the fight against antimicrobial resistance
Pool Marcos Carbajal, University of San Martin de Porres, Peru
Title : Measles vaccination coverage indicators in 2023 and advance towards measles elimination and eradication by 2030
Pedro Plans Rubio, College of Physicians of Barcelona, Spain