Valley Fever, or coccidioidomycosis, is a fungal infection caused by the inhalation of spores from the soil-dwelling fungi Coccidioides immitis and Coccidioides posadasii. These fungi are endemic to arid regions, particularly in the southwestern United States, Mexico, and parts of Central and South America. The majority of individuals exposed to the spores remain asymptomatic, while others may develop mild flu-like symptoms. In some cases, especially among immunocompromised individuals or those with certain pre-existing conditions, Valley Fever can progress to severe pulmonary or disseminated forms, affecting various organs. The symptoms of Valley Fever range from fever, cough, and fatigue to more severe complications such as pneumonia, skin lesions, and joint pain. Diagnosis often involves serological tests, imaging studies, and, in some cases, culture or molecular methods to detect the fungus. Treatment typically includes antifungal medications, with the choice and duration of therapy depending on the severity of the infection. Valley Fever's impact extends beyond individual health, as its prevalence can affect local communities, economies, and healthcare systems in endemic regions. Climate change and environmental factors may influence the distribution of Coccidioides fungi, potentially leading to changes in the epidemiology of Valley Fever. Public health efforts focus on education, prevention, and early diagnosis to mitigate the impact of this fungal infection in endemic areas.
Title : Extensively drug-resistant bacterial infections: Confronting a global crisis with urgent solutions in prevention, surveillance, and treatment
Yazdan Mirzanejad, University of British Columbia, Canada
Title : Pathogen-derived noncanonical epitopes: Are they valuable targets for novel vaccinations and shall we be concerned about autoimmune responses?
Michele Mishto, Francis Crick Institute, United Kingdom
Title : Bioterrorism through the ages: Historical perspective, emerging threats, and medical countermeasures
Claudia Ferreira, Sorbonne University, France
Title : When acute EBV mimics HIV: A case of false positive p24 antigen and low-level HIV antibody reactivity
Smriti Chaudhary, Imperial College Healthcare NHS Trust, United Kingdom
Title : OnePeru: Peruvian bioinformatics platform to contribute to the fight against antimicrobial resistance
Pool Marcos Carbajal, University of San Martin de Porres, Peru
Title : Measles vaccination coverage indicators in 2023 and advance towards measles elimination and eradication by 2030
Pedro Plans Rubio, College of Physicians of Barcelona, Spain