The process of drug discovery and development for infectious diseases is a multifaceted endeavor that encompasses various stages and disciplines. Initially, researchers embark on the quest for novel therapeutic agents by identifying promising drug targets within microbial pathogens. Utilizing cutting-edge technologies such as high-throughput screening and computational modeling, scientists screen vast libraries of compounds to pinpoint potential candidates with antimicrobial activity. Subsequently, selected compounds undergo rigorous preclinical testing to evaluate their safety, efficacy, and pharmacokinetic properties. Upon successful validation, promising candidates progress to clinical trials, where their therapeutic potential is assessed in human subjects. Throughout this journey, collaboration between academia, pharmaceutical companies, and regulatory agencies is essential to navigate the complex regulatory landscape and bring effective treatments to market, addressing the urgent global need for innovative therapies to combat infectious diseases.
Title : Extensively drug-resistant bacterial infections: Confronting a global crisis with urgent solutions in prevention, surveillance, and treatment
Yazdan Mirzanejad, University of British Columbia, Canada
Title : Pathogen-derived noncanonical epitopes: Are they valuable targets for novel vaccinations and shall we be concerned about autoimmune responses?
Michele Mishto, Francis Crick Institute, United Kingdom
Title : Bioterrorism through the ages: Historical perspective, emerging threats, and medical countermeasures
Claudia Ferreira, Sorbonne University, France
Title : A rare case of meningitis and septicemia due to Streptococcus acidominimus
Percival C Dilla, Region II Trauma and Medical Center, Philippines
Title : Detection and variant characterization of lumpy skin disease virus (LSDV) from dairy cattle in India
Manali Bajpai, CSIR-National Chemical Laboratory, India
Title : Acceptability of mass drug administration for lymphatic filariasis in Baglung municipality of Nepal: A mixed-method study
Muskan Pudasainee, Pokhara University, Nepal