Microorganisms are microscopic living organisms that include bacteria, viruses, fungi, and protozoa. While many microorganisms play crucial roles in various ecological processes and human health, some can cause infections and diseases. Antimicrobials are substances that inhibit or kill the growth of microorganisms, and they are essential in the prevention and treatment of infectious diseases. Antibiotics are a common class of antimicrobials that specifically target bacteria. These drugs disrupt bacterial cell walls, protein synthesis, or other essential processes, effectively eliminating the infection. However, the misuse and overuse of antibiotics have led to the development of antibiotic-resistant strains of bacteria, posing a significant global health threat. Antivirals are another category of antimicrobials designed to combat viral infections. Unlike antibiotics, antivirals work by targeting specific stages of the viral life cycle, such as viral entry or replication. They are crucial in managing viral diseases like influenza, HIV, and herpes. Antifungals are antimicrobial agents that combat fungal infections. Fungi, such as Candida and Aspergillus, can cause infections in various tissues and organs. Antifungals work by disrupting fungal cell membranes or inhibiting essential enzymes, preventing the growth and spread of the fungi. In recent years, there has been a growing interest in the development of alternative antimicrobial strategies, including probiotics, phage therapy, and antimicrobial peptides. Probiotics involve the use of beneficial bacteria to promote a healthy microbial balance in the body, while phage therapy utilizes bacteriophages (viruses that infect bacteria) to target and eliminate bacterial infections.
Title : Extensively drug-resistant bacterial infections: Confronting a global crisis with urgent solutions in prevention, surveillance, and treatment
Yazdan Mirzanejad, University of British Columbia, Canada
Title : Pathogen-derived noncanonical epitopes: Are they valuable targets for novel vaccinations and shall we be concerned about autoimmune responses?
Michele Mishto, Francis Crick Institute, United Kingdom
Title : Bioterrorism through the ages: Historical perspective, emerging threats, and medical countermeasures
Claudia Ferreira, Sorbonne University, France
Title : A rare case of meningitis and septicemia due to Streptococcus acidominimus
Percival C Dilla, Region II Trauma and Medical Center, Philippines
Title : Detection and variant characterization of lumpy skin disease virus (LSDV) from dairy cattle in India
Manali Bajpai, CSIR-National Chemical Laboratory, India
Title : Acceptability of mass drug administration for lymphatic filariasis in Baglung municipality of Nepal: A mixed-method study
Muskan Pudasainee, Pokhara University, Nepal