Actinomyces gerencseriae is a Gram-positive, anaerobic bacterium that belongs to the Actinomyces genus. While Actinomyces species are commonly found in the oral cavity and gastrointestinal tract, Actinomyces gerencseriae is specifically associated with human clinical infections. It has been implicated in a variety of infections, including cervicofacial actinomycosis, an infection that primarily affects the head and neck regions. Cervicofacial actinomycosis caused by Actinomyces gerencseriae typically presents as slowly progressing, indurated abscesses or masses, often with draining sinuses. The infection is characterized by the formation of sulfur granules, which are microscopic colonies of the bacterium. Diagnosis involves clinical evaluation, imaging studies, and often, microscopic examination of purulent material. Treatment of Actinomyces gerencseriae infections typically requires a prolonged course of antibiotics, such as penicillin or amoxicillin. Surgical drainage or excision of abscesses may be necessary in some cases. The prognosis is generally favorable with appropriate and timely intervention, but delays in diagnosis and treatment can lead to chronic, debilitating disease.