The surge in Antifungal Resistance is a pressing issue within the realm of antimicrobials, demanding urgent attention and concerted efforts to curb its consequences. As fungi evolve, they develop mechanisms to withstand the effects of antifungal drugs, posing a serious threat to global health. The intricate interplay of factors, including widespread use of antifungal agents, environmental influences, and the adaptability of fungal pathogens, contributes to the complex landscape of antifungal resistance. Antifungal resistance not only complicates the treatment of common fungal infections but also hampers the management of life-threatening conditions, particularly in immunocompromised individuals. The emergence of multidrug-resistant fungal strains raises concerns about the limited options available for effective therapeutic interventions. Addressing antifungal resistance necessitates a multifaceted approach, encompassing enhanced surveillance, judicious use of antifungal medications, and the development of innovative treatment modalities. Global collaboration and knowledge-sharing are vital to stay ahead of the evolving landscape of antifungal resistance and to secure effective treatment options for patients in need.
Title : Extensively drug-resistant bacterial infections: Confronting a global crisis with urgent solutions in prevention, surveillance, and treatment
Yazdan Mirzanejad, University of British Columbia, Canada