Antimicrobial peptides (AMPs) constitute an integral part of the body's defense arsenal, showcasing remarkable versatility in combating infectious agents. These peptides are produced by various organisms, including humans, as a rapid response to microbial threats. Their multifaceted mechanisms of action involve disrupting microbial membranes, inhibiting protein and nucleic acid synthesis, and modulating the host immune response. AMPs demonstrate a unique ability to selectively target pathogens while sparing host cells, minimizing the risk of side effects. Their effectiveness against a broad spectrum of microorganisms, including antibiotic-resistant strains, positions AMPs as potential game-changers in the fight against emerging infectious diseases. Research efforts are underway to harness the therapeutic potential of AMPs in medical applications, ranging from topical treatments for skin infections to systemic therapies for more severe conditions. As our understanding of AMPs continues to evolve, unlocking their full therapeutic potential holds promise for addressing the challenges posed by antimicrobial resistance.