An immunocompromised host refers to an individual whose immune system is weakened, rendering them more susceptible to infections and illnesses. Various factors can lead to immunocompromise, including medical conditions like HIV/AIDS, autoimmune disorders, cancer, organ transplantation, and certain medications such as corticosteroids and chemotherapy drugs. In immunocompromised individuals, the body's ability to defend against pathogens is compromised, increasing the risk of severe or opportunistic infections. As a result, healthcare providers must exercise heightened vigilance when caring for immunocompromised patients, implementing stringent infection control measures and tailoring treatment strategies to mitigate the risk of complications. Additionally, immunocompromised individuals may require specialized medical interventions, such as prophylactic antimicrobial therapy or immunomodulatory agents, to bolster their immune function and reduce susceptibility to infections.