In the realm of Microbial Biogeochemistry, the study of antimicrobials is a multifaceted exploration encompassing microbial interactions with geochemical cycles. Antimicrobials, whether naturally occurring or introduced into environments through human activities, have profound effects on microbial communities and their functions. Microbial Biogeochemistry unravels the intricate web of relationships between microorganisms and antimicrobials, shedding light on the mechanisms influencing antimicrobial fate, transport, and transformation in soils, water, and sediments. This interdisciplinary field strives to deepen our understanding of the ecological repercussions of antimicrobial presence, addressing key questions about microbial responses and their implications for environmental and human health.