While antibiotics are the primary treatment for UTIs, the rising concern of antibiotic resistance poses challenges in managing these infections effectively. Overuse and misuse of antibiotics contribute to the development of resistant strains of bacteria, making it crucial to prescribe antibiotics judiciously and according to susceptibility testing. Researchers are exploring alternative treatment options, including novel antibiotics and preventive measures, to address the growing threat of antibiotic resistance in UTIs. Preventing UTIs involves various strategies, such as staying hydrated, maintaining good hygiene practices, and emptying the bladder regularly. Cranberry products, though popularly believed to prevent UTIs, have shown mixed results in research studies. Ongoing research explores the role of the microbiome in urinary health and the development of probiotics as potential preventive measures. Special populations, such as pregnant women and individuals with recurrent UTIs, require tailored management approaches. Pregnancy increases the risk of complications, making prompt diagnosis and appropriate treatment crucial. For individuals prone to recurrent UTIs, prophylactic antibiotics or other preventive strategies may be considered under medical supervision.